We performed a retrospective analysis of cases in which polypectomy was performed with the Duckbill polyp snare and a prospective pain analysis in patients undergoing office-based hysteroscopy using a visual analog scale (VAS, range 0-10). The patients, both pre- and postmenopausal, underwent office hysteroscopy for abnormal uterine bleeding. In all, 116 cases of endometrial polyps were diagnosed and removed with the Duckbill polyp snare. This technique was easy to set up and allowed therapeutic hysteroscopy in a see-and-treat fashion during office hysteroscopy. In 188 patients, pain was evaluated using a VAS. Polypectomy with the Duckbill snare was well tolerated by patients, with a pain score of 4.8 compared with a pain score of 4.2 for diagnostic hysteroscopy. Therefore, we conclude that the Duckbill polyp snare is useful for operative office hysteroscopy and is well tolerated by patients.