[Efficient synthesis of 3'-amino-3'-deoxythymidine derivatives]

Bioorg Khim. 2005 Mar-Apr;31(2):147-50. doi: 10.1007/s11171-005-0018-4.
[Article in Russian]

Abstract

An efficient method of reduction of 3'-azido-3'-deoxythymidine and its 5'-protected derivatives to 3'-aminothymidine derivatives on a palladium catalyst using ammonium formate as a source of hydrogen was suggested.

Publication types

  • English Abstract

MeSH terms

  • Chromatography
  • Dideoxynucleosides / chemical synthesis*
  • Magnetic Resonance Spectroscopy

Substances

  • Dideoxynucleosides
  • 3'-aminothymidine