Glucagon like peptide-1 is protective against myocardial ischemia/reperfusion injury when given either as a preconditioning mimetic or at reperfusion in an isolated rat heart model

Cardiovasc Drugs Ther. 2005 Jan;19(1):9-11. doi: 10.1007/s10557-005-6892-4.

Authors

Amal K Bose¹, Mihaela M Mocanu, Richard D Carr, Derek M Yellon

Affiliation

¹ The Hatter Institute and Centre for Cardiology, University College London Hospital & Medical School, London, UK.

PMID: 15883751
DOI: 10.1007/s10557-005-6892-4

No abstract available

MeSH terms

Animals
Cardiotonic Agents / administration & dosage
Cardiotonic Agents / pharmacology*
Glucagon / administration & dosage
Glucagon / pharmacology*
Glucagon-Like Peptide 1
Humans
In Vitro Techniques
Ischemic Preconditioning, Myocardial*
Male
Myocardial Reperfusion
Myocardial Reperfusion Injury / prevention & control*
Peptide Fragments / administration & dosage
Peptide Fragments / pharmacology*
Protein Precursors / administration & dosage
Protein Precursors / pharmacology*
Rats
Rats, Sprague-Dawley
Time Factors

Substances

Cardiotonic Agents
Peptide Fragments
Protein Precursors
Glucagon-Like Peptide 1
Glucagon