Abstract
The authors reviewed 37 patients with leptomeningeal metastasis (LM) who required a ventriculoperitoneal shunt (VP shunt) for management of intracranial hypertension. Improvement was seen in 27 (77%) patients; subdural hematoma developed in one and shunt malfunction in three. Median overall survival was 2 months (range 2 days to 3.6 years) after VP shunt placement, but there was no procedure-related mortality. The prognosis of LM remained poor, but VP shunt can be an effective palliative tool when required.
MeSH terms
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Adult
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Aged
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Aged, 80 and over
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Brain / pathology
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Brain / physiopathology
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Brain Neoplasms / secondary
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Breast Neoplasms / pathology
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Breast Neoplasms / radiotherapy
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Carcinoma / complications*
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Carcinoma / secondary
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Female
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Humans
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Hydrocephalus / etiology
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Hydrocephalus / physiopathology
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Hydrocephalus / surgery
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Intracranial Hypertension / etiology
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Intracranial Hypertension / physiopathology
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Intracranial Hypertension / surgery*
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Lung Neoplasms / pathology
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Lung Neoplasms / radiotherapy
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Magnetic Resonance Imaging
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Male
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Meningeal Neoplasms / complications*
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Meningeal Neoplasms / secondary
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Middle Aged
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Neoplasm Metastasis / pathology
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Neoplasm Metastasis / physiopathology*
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Palliative Care / standards
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Palliative Care / trends
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Prognosis
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Subarachnoid Space / pathology
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Subarachnoid Space / physiopathology
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Subarachnoid Space / surgery*
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Survival Rate
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Tomography, X-Ray Computed
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Treatment Outcome
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Ventriculoperitoneal Shunt / standards*
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Ventriculoperitoneal Shunt / trends