Cytogenetic t(11;17)(q13;q21) in a pediatric ependymoma. Is 11q13 a recurring breakpoint in ependymomas?

L Sainati; A Montaldi; M C Putti; F Giangaspero; L Rigobello; M Stella; L Zanesco; G Basso

doi:10.1016/0165-4608(92)90218-w

Cytogenetic t(11;17)(q13;q21) in a pediatric ependymoma. Is 11q13 a recurring breakpoint in ependymomas?

Cancer Genet Cytogenet. 1992 Apr;59(2):213-6. doi: 10.1016/0165-4608(92)90218-w.

Authors

L Sainati¹, A Montaldi, M C Putti, F Giangaspero, L Rigobello, M Stella, L Zanesco, G Basso

Affiliation

¹ Pediatric Department, University of Padova, Italy.

PMID: 1581886
DOI: 10.1016/0165-4608(92)90218-w

Abstract

Cytogenetic studies on a supratentorial ependymoma from a 1-year-old boy showed a t(11;17)(q13;q21). This is the second ependymoma reported with a rearrangement at 11q13; to our knowledge the 11q13 is the first recurring breakpoint reported in ependymoma.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Chromosome Banding
Chromosome Fragility*
Chromosomes, Human, Pair 11*
Chromosomes, Human, Pair 17*
Ependymoma / genetics*
Ependymoma / pathology
Glial Fibrillary Acidic Protein / analysis
Humans
Immunohistochemistry
Infant
Male
Supratentorial Neoplasms / genetics*
Supratentorial Neoplasms / pathology
Translocation, Genetic*

Substances

Glial Fibrillary Acidic Protein