Biocatalytic racemisation of alpha-hydroxycarboxylic acids at physiological conditions

Chem Commun (Camb). 2005 Apr 14:(14):1904-5. doi: 10.1039/b418786e. Epub 2005 Feb 9.

Abstract

Biocatalytic racemisation of aliphatic, aryl-aliphatic and aromatic alpha-hydroxycarboxylic acids was accomplished using whole resting cells of Lactobacillus paracasei DSM 20207; the mild (physiological) reaction conditions ensured an essentially 'clean' isomerization in the absence of side reactions, such as elimination or decomposition.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carboxylic Acids / chemistry*
  • Catalysis
  • Isomerism
  • Lactobacillus / chemistry
  • Lactobacillus / metabolism
  • Molecular Structure
  • Oxidation-Reduction

Substances

  • Carboxylic Acids