Abstract
Enzymatic modifications of split and mix libraries were followed by "pulling down" onto a 2-dimensional DNA microarray, via PNA tagging; this allowed complete library interrogation of all members of the split and mix library.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Combinatorial Chemistry Techniques / methods*
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Molecular Structure
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Oligonucleotide Array Sequence Analysis*
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Peptide Hydrolases / chemistry
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Peptide Nucleic Acids*
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Proto-Oncogene Proteins c-abl / chemistry
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Solutions / chemistry
Substances
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Peptide Nucleic Acids
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Solutions
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Proto-Oncogene Proteins c-abl
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Peptide Hydrolases