[Studies on the preparation technology of beta-cyclodextrin inclusion compound for chuanxiong volatile oil extracted with CO2 supercritical fluid]

Zhongguo Zhong Yao Za Zhi. 2004 Jan;29(1):39-41.
[Article in Chinese]

Abstract

Objective: To explore the preparation technology of beta-cyclodextrin inclusion compound for chuanxiong volatile oil.

Method: Orthogonal test was used to evaluate the influence of the 4 factors, including the proportion of volatile oil to beta-cyclodextrin, the mode of mixing, inclusion temperature and mixing time.

Result: The best inclusion condition is the proportion of volatile oil to beta-cyclodextrin 1:9, the mode of mixing grinding, inclusion temperature 60 degrees C and inclusion time 90 min.

Conclusion: The best inclusion technology of chuanxiong volatile oil is confirmed.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Carbon Dioxide
  • Chromatography, Supercritical Fluid
  • Drug Carriers
  • Ligusticum / chemistry*
  • Oils, Volatile / administration & dosage*
  • Oils, Volatile / isolation & purification
  • Plant Roots / chemistry
  • Plants, Medicinal / chemistry
  • Technology, Pharmaceutical / methods*
  • Temperature
  • Time Factors
  • beta-Cyclodextrins*

Substances

  • Drug Carriers
  • Oils, Volatile
  • beta-Cyclodextrins
  • Carbon Dioxide