Pathogenesis of pulmonary arterial hypertension: the need for multiple hits

Circulation. 2005 Feb 8;111(5):534-8. doi: 10.1161/01.CIR.0000156326.48823.55.
No abstract available

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.
  • Comment

MeSH terms

  • Bone Morphogenetic Protein Receptors, Type II
  • Genetic Predisposition to Disease
  • Humans
  • Hypertension, Pulmonary / etiology
  • Hypertension, Pulmonary / genetics*
  • Microsatellite Repeats
  • Mutation
  • Polymorphism, Genetic
  • Protein Serine-Threonine Kinases / genetics*
  • Pulmonary Artery / cytology
  • Pulmonary Artery / metabolism
  • Signal Transduction

Substances

  • Protein Serine-Threonine Kinases
  • BMPR2 protein, human
  • Bone Morphogenetic Protein Receptors, Type II