Clinicomorphological correlations are presented for 136 patients with idiopathic and immunosuppressive types of Kaposi's sarcoma (KS) with spot, plaque and tumour manifestations. Early symptoms of KS (spot stage) as well as regressed and angiomatous elements are difficult for pathomorphological diagnosis which should be performed regarding clinico-anamnestic data. The help in the diagnosis may be observation of DNA HHV-8 sequenses in PCR from tissue biopsies and positive immunohistochemical reaction of endotheliocytes and fusiform tumour cell to CD34.