[Homocystein and cardiovascular risk: is dosage useful?]

Praxis (Bern 1994). 2004 Dec 8;93(50):2093-7. doi: 10.1024/0369-8394.93.50.2093.
[Article in French]

Abstract

Hyperhomocysteinemia represents an independent risk factor for atherothrombotic disease. Physiopathological mechanisms of accelerated progression of atherosclerosis in presence of hyperhomocysteinemia are complex. Herein we report a clinical case which emphasis the importance of screening elevated homocystein in the absence of conventional risk factors in patients who suffer from premature atherosclerosis.

MeSH terms

  • Adult
  • Coronary Artery Disease / blood*
  • Coronary Artery Disease / diagnosis
  • Coronary Artery Disease / genetics
  • DNA Mutational Analysis
  • Genetic Carrier Screening
  • Homocysteine / blood*
  • Humans
  • Male
  • Methylenetetrahydrofolate Reductase (NADPH2) / genetics
  • Myocardial Infarction / blood*
  • Myocardial Infarction / diagnosis
  • Myocardial Infarction / genetics
  • Protein S Deficiency / blood
  • Protein S Deficiency / diagnosis
  • Protein S Deficiency / genetics
  • Prothrombin / genetics
  • Recurrence
  • Risk Factors
  • Thrombophilia / blood
  • Thrombophilia / diagnosis
  • Thrombophilia / genetics

Substances

  • Homocysteine
  • Prothrombin
  • Methylenetetrahydrofolate Reductase (NADPH2)