Patient-specific dose and radiation risk estimation in pediatric cardiac catheterization

Circulation. 2005 Jan 4;111(1):83-9. doi: 10.1161/01.CIR.0000151098.52656.3A. Epub 2004 Dec 20.

Abstract

Background: Because of the higher radiosensitivity of infants and children compared with adults, there is a need to evaluate the doses delivered to pediatric patients who undergo interventional cardiac procedures. However, knowledge of the effective dose in pediatric interventional cardiology is very limited.

Methods and results: For an accurate risk estimation, a patient-specific Monte Carlo simulation of the effective dose was set up in 60 patients with congenital heart disease who underwent diagnostic (n=28) or therapeutic (n=32) cardiac catheterization procedures. The dose-saving effect of using extra copper filtration in the x-ray beam was also investigated. For diagnostic cardiac catheterizations, a median effective dose of 4.6 mSv was found. Therapeutic procedures resulted in a higher median effective dose of 6.0 mSv because of the prolonged use of fluoroscopy. The overall effect of inserting extra copper filtration into the x-ray beam was a total effective dose reduction of 18% with no detrimental effect on image quality. An excellent correlation between the dose-area product and effective patient dose was found (r=0.95). Hence, dose-area product is suitable for online estimation of the effective dose with good accuracy. With all procedures included, the resulting median lifetime risk for stochastic effects was 0.08%.

Conclusions: Because of the high radiation exposure, it is important to monitor patient dose by dose-area product instrumentation and to use additional beam filtration to keep the effective dose as low as possible in view of the sensitivity of the pediatric patients.

MeSH terms

  • Cardiac Catheterization* / adverse effects
  • Child
  • Child, Preschool
  • Computer Simulation
  • Copper
  • Dose-Response Relationship, Radiation
  • Equipment Design
  • Female
  • Fluoroscopy / adverse effects
  • Heart Defects, Congenital / diagnosis
  • Heart Defects, Congenital / surgery
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Monte Carlo Method
  • Phantoms, Imaging
  • Radiation Dosage
  • Radiation Injuries / epidemiology
  • Radiation Injuries / etiology
  • Radiology, Interventional
  • Radiometry*
  • Risk
  • Risk Assessment
  • Skin / radiation effects
  • Stochastic Processes
  • Thermoluminescent Dosimetry

Substances

  • Copper