[Optical coherence tomography and ARMD]

J Fr Ophtalmol. 2004 Nov;27(9 Pt 2):3S7-30.
[Article in French]

Abstract

Optical coherent tomography examination (OCT) is a new medical diagnostic imaging modality analogous to ultrasound B-mode imaging, able to perform anteroposterior cross-sectional imaging of interior tissues and is useful in clinical practice in ARMD. The combination of fluorescein and ICG angiography imaging with OCT imaging will bring additional information for all clinical forms of ARMD. Many patterns and images are easy to identify, including serous retinal detachment, diffuse or cystoid retinal edema, serous or fibrovascular retinal pigment epithelium detachment with or without retinal pigment epithelium (RPE) tears and fibrosis. Other symptoms are more difficult to detect and to analyze and will need to be combined with other imaging techniques: the presence of choroidal new vessels and their localisation related to the center of the fovea and the RPE; the association of different lesions (hemorrhages, exudation, fibrosis, anastomosis and PE detachment) and recognition of less frequent lesions such as polypoidal choroidal vasculopathy. During follow-up, choroidal new vessels may be shown with different modalities. OCT examination could detect and localize these lesions, helping to determine the best management strategy. OCT examination appears to be particularly useful for both detection of persistent fluid and reabsorption and reattachment of the retina.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Aged
  • Choroidal Neovascularization / diagnosis
  • Diagnosis, Differential
  • Female
  • Fluorescein Angiography
  • Follow-Up Studies
  • Humans
  • Indocyanine Green / analogs & derivatives*
  • Infrared Rays
  • Laser Coagulation
  • Macular Degeneration / diagnosis*
  • Macular Degeneration / drug therapy
  • Macular Degeneration / surgery
  • Macular Edema / diagnosis
  • Male
  • Photochemotherapy
  • Retinal Drusen / diagnosis
  • Time Factors
  • Tomography, Optical Coherence* / instrumentation
  • Tomography, Optical Coherence* / methods

Substances

  • Infracyanine green
  • Indocyanine Green