[Anastrozole-resistant breast cancer responsive to exemestane--a case report]

Gan To Kagaku Ryoho. 2004 Nov;31(12):2051-3.
[Article in Japanese]

Abstract

We describe a postmenopausal woman suffering from advanced breast cancer with pleural effusion. She had prior anastrozole therapy, and was referred to our hospital with dyspnea. The use of exemestane, a highly selective steroidal aromatase inhibitor (25 mg daily), successfully induced remission of pleural effusion. Exemestane is a useful treatment for postmenopausal woman with advanced breast cancer, which is refractory to anastrozole.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anastrozole
  • Androstadienes / therapeutic use*
  • Aromatase Inhibitors / therapeutic use*
  • Breast Neoplasms / drug therapy*
  • Breast Neoplasms / pathology
  • Carcinoma, Ductal, Breast / drug therapy*
  • Carcinoma, Ductal, Breast / pathology
  • Drug Resistance, Neoplasm*
  • Female
  • Humans
  • Nitriles / pharmacology*
  • Postmenopause
  • Triazoles / pharmacology*

Substances

  • Androstadienes
  • Aromatase Inhibitors
  • Nitriles
  • Triazoles
  • Anastrozole
  • exemestane