Pure post-stroke cerebellar cognitive affective syndrome: a case report

Neurol Sci. 2004 Oct;25(4):220-4. doi: 10.1007/s10072-004-0325-1.

Abstract

Cerebellar pathology commonly shows important motor signs and less evident cognitive dysfunction. The 'cerebellar cognitive affective syndrome' is characterised by impairment on executive function, spatial cognition, language and behaviour. We report the case of a man with acute onset of transitory motor features and severe mental disorders. Cranial CT and brain MRI revealed extended cerebellar lesions. Neuropsychological assessment disclosed deficits of attention, executive function and memory. Auditory event-related potentials showed abnormal P300. These data suggest a pure "cerebellar cognitive affective syndrome"and strengthen the hypothesis of cerebellar cognitive function modulation.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Attention / physiology
  • Cerebellar Diseases / etiology*
  • Cerebellar Diseases / pathology
  • Cerebellar Diseases / psychology
  • Cerebellum / diagnostic imaging
  • Cerebellum / pathology
  • Cerebellum / physiopathology*
  • Cognition Disorders / etiology*
  • Cognition Disorders / pathology
  • Cognition Disorders / psychology
  • Event-Related Potentials, P300 / physiology
  • Humans
  • Language Disorders / etiology
  • Language Disorders / pathology
  • Language Disorders / psychology
  • Magnetic Resonance Imaging
  • Male
  • Memory Disorders / complications
  • Memory Disorders / pathology
  • Memory Disorders / psychology
  • Mood Disorders / etiology*
  • Mood Disorders / pathology
  • Mood Disorders / psychology
  • Neuropsychological Tests
  • Stroke / complications*
  • Stroke / pathology
  • Stroke / psychology
  • Tomography, X-Ray Computed