Abstract
Among 99 clinical Klebsiella pneumoniae isolates resistant to cefoxitin and extended-spectrum cephalosporins, coexistence of AmpC (DHA-1, CMY-2, or CMY-8) and extended-spectrum beta-lactamases (CTX-M and/or SHV) was detected in a total of 35. The remainder produced AmpC (n = 42), extended-spectrum beta-lactamases (n = 9), metallo-beta-lactamases (n = 2), or none of these enzymes (n = 11). Phenotypic characteristics of these isolates were demonstrated.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology
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Cephalosporin Resistance / genetics*
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Cephalosporins / pharmacology
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Cephamycins / pharmacology
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DNA, Bacterial / analysis
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Electrophoresis, Gel, Pulsed-Field
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Hospitals, Teaching*
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Humans
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Klebsiella Infections / epidemiology
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Klebsiella Infections / microbiology
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Klebsiella pneumoniae / classification*
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Klebsiella pneumoniae / drug effects*
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Klebsiella pneumoniae / genetics
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Klebsiella pneumoniae / isolation & purification
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Microbial Sensitivity Tests
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Phenotype
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Taiwan / epidemiology
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beta-Lactamases / genetics*
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beta-Lactamases / metabolism
Substances
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Anti-Bacterial Agents
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Cephalosporins
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Cephamycins
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DNA, Bacterial
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beta-Lactamases