A clinically meaningful difference was generated for a performance measure of recovery from hip fracture

J Clin Epidemiol. 2004 Oct;57(10):1019-24. doi: 10.1016/j.jclinepi.2004.02.010.

Abstract

Background and objective: The Lower Extremity Gain Scale (LEGS) is a performance measure of tasks that are often impaired in hip fracture patients. This study was designed to determine a clinically meaningful difference in LEGS.

Methods: The population was 139 female patients (age >65 years) admitted to Baltimore hospitals. Recovery levels were estimated by fitting trajectory curves for the cohort for the 12 months post fracture. The clinically meaningful difference was evaluated using an anchor-based approach, examining the relationship between the LEGS recovery level and age. A second, distribution-based method used an effect size of .20.

Results: According to our model, a difference of 5 years in age corresponded to a difference of 1.6-3.6 points in LEGS scores. The standard deviation for LEGS at 12 months was 8.0; thus, Cohen's effect size of 0.2 would equate to a difference of 1.6 points.

Conclusion: This suggests that a clinically meaningful difference in the LEGS scores for a population in this age range would be 2-3 points.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Activities of Daily Living
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Female
  • Health Status Indicators*
  • Hip Fractures / rehabilitation*
  • Hip Joint / physiopathology
  • Humans
  • Recovery of Function
  • Sensitivity and Specificity
  • Treatment Outcome