Two novel dicoumaro-p-menthanes from Gerbera piloselloides (L.) CASS

Chem Pharm Bull (Tokyo). 2004 Nov;52(11):1362-4. doi: 10.1248/cpb.52.1362.

Abstract

Two new type dicoumarins (dicoumaro-p-menthanes), named dibothrioclinins I (1) and II (2) were isolated from the roots and rhizomes of Gerbera piloselloides (L.) CASS., collected in Yunnan Province, China. Their structures were elucidated on the basis of MS, 1D ((1)H-NMR, (13)C-NMR, DEPT and NOE) and 2D ((1)H-(1)H COSY, HMQC, HMBC) NMR spectral analyses. The relative structures of the two compounds were established by NOE difference spectroscopy and further confirmed by single-crystal X-ray diffraction studies.

MeSH terms

  • Asteraceae*
  • Dicumarol / chemistry*
  • Dicumarol / isolation & purification*
  • Drugs, Chinese Herbal / chemistry*
  • Drugs, Chinese Herbal / isolation & purification*
  • Plant Roots
  • Rhizome

Substances

  • Drugs, Chinese Herbal
  • Dicumarol