[Pancreatic tumor revealed by metastatic bilateral ovarian tumor with virilisation syndrome]

Gynecol Obstet Fertil. 2004 Oct;32(10):860-2. doi: 10.1016/j.gyobfe.2004.08.017.
[Article in French]

Abstract

We report a case of a 38-year-old patient presenting with both pancreatic and a bilateral ovarian tumor revealed by a virilization syndrome. Clinically, both tumors were conceivably distinct. However, on histological examination, they were found to be morphologically similar, with neuroendocrine features, suggesting that pancreatic tumor was a primitive neoplasm and the ovarian one a metastatic spread of that lesion. The virilization syndrome was due to the functional status of the ovarian tumors that was confirmed by immunohistochemical detection of inhibin.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Humans
  • Immunohistochemistry
  • Neuroendocrine Tumors / metabolism*
  • Neuroendocrine Tumors / pathology
  • Neuroendocrine Tumors / secondary
  • Ovarian Neoplasms / pathology
  • Ovarian Neoplasms / secondary*
  • Pancreatic Neoplasms / pathology*
  • Syndrome
  • Virilism / etiology