[The positive effect of sildenafil on LUTS from BPH while treating ED]

Zhonghua Nan Ke Xue. 2004 Sep;10(9):681-3.
[Article in Chinese]

Abstract

Objective: To explore the possible relationship between erectile dysfunction (ED) and benign prostate hyperplasia (BPH) in men, and to assess the positive effect of Sildenafil on the lower urinary tract symptoms (LUTS) from BPH while treating ED.

Methods: Thirty-two patients with ED and BPH were offered oral Sildenafil and reviewed before and six months after the administration of Sildenafil by the International Index of Erectile Function-5 (IIEF-5) and the International Prostate Symptom Score (IPSS) questionnaires. Scores were tested by chi-square.

Results: IIEF-5 scores were increased by 42.36% and IPSS scores declined by 20.14%, with statistical significance (P < 0.01).

Conclusion: Treatment of ED with Sildenafil appears to improve urinary symptom scores. A lower IPSS at baseline seems to predict a better response to Sildenafil therapy for ED.

Publication types

  • Controlled Clinical Trial
  • English Abstract

MeSH terms

  • Aged
  • Erectile Dysfunction / drug therapy*
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Phosphodiesterase Inhibitors / therapeutic use*
  • Piperazines / therapeutic use*
  • Prostatic Hyperplasia / complications
  • Purines / therapeutic use
  • Sildenafil Citrate
  • Sulfones / therapeutic use*
  • Surveys and Questionnaires
  • Urination Disorders / drug therapy*
  • Urination Disorders / etiology

Substances

  • Phosphodiesterase Inhibitors
  • Piperazines
  • Purines
  • Sulfones
  • Sildenafil Citrate