Abstract
[reaction: see text] Olefin cross-metathesis has been used to prepare alpha-C-galactosylceramide derivatives. The metathesis process merged vinyl and propenyl glycosides with vinyl derivatives of phytosphingosine. The use of ethylene enhanced the yield of the methathesis step.
Publication types
-
Research Support, N.I.H., Extramural
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Adjuvants, Immunologic / chemical synthesis*
-
Adjuvants, Immunologic / pharmacology
-
Alkenes / chemistry*
-
Ethylenes / chemistry*
-
Galactosylceramides / chemical synthesis*
-
Galactosylceramides / pharmacology
-
Glycosides / chemistry
-
Molecular Structure
-
Sphingosine / analogs & derivatives
-
Vinyl Compounds / chemistry
Substances
-
Adjuvants, Immunologic
-
Alkenes
-
Ethylenes
-
Galactosylceramides
-
Glycosides
-
Vinyl Compounds
-
ethylene
-
Sphingosine