A novel strategy for the preparation of arylhydroxylamines: chemoselective reduction of aromatic nitro compounds using bakers' yeast

Feng Li; Jingnan Cui; Xuhong Qian; Rong Zhang

doi:10.1039/b408566c

A novel strategy for the preparation of arylhydroxylamines: chemoselective reduction of aromatic nitro compounds using bakers' yeast

Chem Commun (Camb). 2004 Oct 21:(20):2338-9. doi: 10.1039/b408566c. Epub 2004 Sep 7.

Authors

Feng Li¹, Jingnan Cui, Xuhong Qian, Rong Zhang

Affiliation

¹ State Key Laboratory of Fine Chemicals, Dalian University of Technology, China.

PMID: 15490009
DOI: 10.1039/b408566c

Abstract

Using bakers' yeast as a biocatalyst, the chemoselective reduction of aromatic nitro compounds bearing electron-withdrawing groups gave the corresponding hydroxylamines with good to excellent conversion under mild conditions.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chromatography, High Pressure Liquid
Hydroxylamines / chemical synthesis*
Nitro Compounds / chemistry*
Oxidation-Reduction
Saccharomyces cerevisiae / chemistry*

Substances

Hydroxylamines
Nitro Compounds