[Polypeptide growth factors in embryogenesis and tumor growth]

Ontogenez. 2004 Jul-Aug;35(4):254-72.
[Article in Russian]

Abstract

Polypeptide growth factors, which belong to different families (epidermal growth factors, insulin-like growth factors, fibroblast growth factors, transforming growth factors-beta, and some others), were characterized regarding their specific role in embryogenesis and tumor growth. Differences and parallels of the functioning of growth factors in these processes have been noted. Potential significance of the described characteristics of growth factors for directed modulation of embryogenesis and tumor growth is discussed.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Animals
  • Embryonic Development / genetics
  • Embryonic Development / physiology*
  • Humans
  • Intercellular Signaling Peptides and Proteins / genetics
  • Intercellular Signaling Peptides and Proteins / metabolism
  • Intercellular Signaling Peptides and Proteins / physiology*
  • Neoplasms / etiology*
  • Neoplasms / genetics
  • Neoplasms / pathology

Substances

  • Intercellular Signaling Peptides and Proteins