The combined use of cholesterol-lowering drugs and cholesterol-lowering bread spreads: health behavior data from Finland

Prev Med. 2004 Nov;39(5):849-55. doi: 10.1016/j.ypmed.2004.03.016.

Abstract

Background: Cholesterol-lowering drugs may metabolically interact with cholesterol-lowering bread spreads. This study analyses the prevalence of use of drugs, bread spreads or the combination of both in people aware of their high/elevated cholesterol level, and compares users of the three therapies on health behavior and demographics.

Methods: Participants (9581, 25-74 years) from The National FINRISK 2002 Study filled out a questionnaire on demographics and health (related) issues. Blood samples, blood pressure, body weight and height were measured.

Results: Of those who reported to have a high cholesterol level (31% of the study population), 19% used cholesterol-lowering drugs, 11% used cholesterol-lowering bread spreads and 5% combined both therapies. On a population level, only 1% jointly used a drug and bread spread therapy. The combination was used by especially highly educated people and those having a healthy diet.

Conclusion: Combining a cholesterol-lowering drug with a bread spread regimen is relatively rare, even among those being aware of their high cholesterol levels. The combined usage was most frequent among 'the better off'. Public health risks of a metabolic interaction between both therapies may not be of major importance yet, but future follow-up is recommended.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Distribution
  • Aged
  • Anticholesteremic Agents / administration & dosage*
  • Bread
  • Cholesterol / blood
  • Dietary Fats / administration & dosage*
  • Drug Therapy, Combination
  • Female
  • Finland / epidemiology
  • Health Behavior*
  • Health Knowledge, Attitudes, Practice
  • Health Surveys
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use
  • Hypercholesterolemia / blood
  • Hypercholesterolemia / epidemiology*
  • Hypercholesterolemia / prevention & control*
  • Male
  • Margarine / statistics & numerical data*
  • Middle Aged
  • Sex Distribution

Substances

  • Anticholesteremic Agents
  • Dietary Fats
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Margarine
  • Cholesterol