Opportunities for nanotechnology-based innovation in tissue proteomics

Biomed Microdevices. 2004 Sep;6(3):231-9. doi: 10.1023/B:BMMD.0000042053.51016.b4.

Abstract

Within this review we discuss two methodologies used in tissue proteomics, namely mass-spectrometry (MS)-based protein pattern diagnostics and protein microarrays. Further, we describe current goals within the field of tissue proteomics and suggest points of departure for designing nanotechnology-based tools that will enhance the role of molecularly based diagnostics and therapeutics development in clinical medicine.

Publication types

  • Review

MeSH terms

  • Animals
  • Biomarkers, Tumor / metabolism
  • Humans
  • Mass Spectrometry / instrumentation
  • Mass Spectrometry / methods*
  • Mass Spectrometry / trends
  • Nanotechnology / instrumentation
  • Nanotechnology / methods*
  • Nanotechnology / trends
  • Neoplasm Proteins / metabolism*
  • Neoplasms / diagnosis*
  • Neoplasms / metabolism*
  • Protein Array Analysis / instrumentation
  • Protein Array Analysis / methods*
  • Protein Array Analysis / trends
  • Proteomics / instrumentation
  • Proteomics / methods*
  • Proteomics / trends
  • Technology Assessment, Biomedical

Substances

  • Biomarkers, Tumor
  • Neoplasm Proteins