Results of a mechanical Duhamel pull-through for the treatment of Hirschsprung's disease and intestinal neuronal dysplasia

J Pediatr Surg. 2004 Sep;39(9):1349-55. doi: 10.1016/j.jpedsurg.2004.05.007.

Abstract

Background/purpose: The authors analyzed the results of a modified entirely mechanical Duhamel pull-through for the treatment of Hirschsprung' disease or type B intestinal neuronal dysplasia. The aim of the follow-up was to evaluate results of a Duhamel procedure entirely performed with the use of staplers.

Methods: Fifty-six patients were followed up to detect complications and outcome. Patients were evaluated clinically, and, when symptoms were present, a suction biopsy with histochemical analysis, an x-ray contrast enema, or an endoscopy was performed.

Results: Early complications developed in 4 cases (7%) including a case of leakage (1.8%). No patient experienced recurrence. During a mean follow-up of 49 months, further complications occurred in 16 other patients: 4 adhesive obstructions requiring surgery, 3 strictures, 5 chronic bleeding, 4 fecaloma formation, 2 urinary problems, and 13 postoperative enterocolitis. Four patients (7%) had more than 3 passages of liquid stools per day, and 3 of them who had an ileal pull-through had constant soiling. Thirty-seven children (68.5%) had 1 to 2 bowel movements per day and were continent. Seven (13%) had less than 3 bowel movements per week. Three children who underwent total colectomy were incontinent (5.5%). Three more children (5.5%) have not yet reached the age for continence. Forty-nine parents (87%) judged the outcome satisfactory.

Conclusions: Follow-up of mechanical Duhamel pull-through showed an acceptable long-term outcome. An increased risk of incontinence is present in case of ileal pull-through, whereas constipation is more frequent after partial colon resection, regardless of the type of intestinal neuronal malformation.

Publication types

  • Evaluation Study

MeSH terms

  • Abnormalities, Multiple
  • Adolescent
  • Child
  • Child, Preschool
  • Colectomy / methods
  • Enteric Nervous System / abnormalities*
  • Enterocolitis / epidemiology
  • Fecal Incontinence / epidemiology
  • Female
  • Follow-Up Studies
  • Gastrointestinal Hemorrhage / epidemiology
  • Hirschsprung Disease / surgery*
  • Humans
  • Ileum / surgery
  • Infant
  • Intestines / abnormalities
  • Intestines / innervation*
  • Male
  • Patient Satisfaction
  • Postoperative Complications / epidemiology
  • Postoperative Complications / surgery
  • Sleep Apnea, Central / complications
  • Surgical Stapling
  • Tissue Adhesions / epidemiology
  • Tissue Adhesions / surgery
  • Treatment Outcome