Generation of the alpha beta T-cell repertoire

C Benoist; D Mathis

doi:10.1016/0952-7915(92)90005-y

Generation of the alpha beta T-cell repertoire

Curr Opin Immunol. 1992 Apr;4(2):156-61. doi: 10.1016/0952-7915(92)90005-y.

Authors

C Benoist¹, D Mathis

Affiliation

¹ CNRS, l'INSERM Institut de Chimie Biologique, Strasbourg, France.

PMID: 1534989
DOI: 10.1016/0952-7915(92)90005-y

Abstract

The sequence of events leading to a diverse and competent alpha beta T-cell repertoire has been known in outline form for some time. Details continue to be sketched in, however, and some of these suggest previously unsuspected influences on repertoire content.

Publication types

Review

MeSH terms

Animals
Gene Rearrangement
Humans
Lymphocyte Subsets / immunology
Receptors, Antigen, T-Cell, alpha-beta / genetics
Receptors, Antigen, T-Cell, alpha-beta / immunology*
T-Lymphocytes / immunology*
Thymus Gland / immunology

Substances

Receptors, Antigen, T-Cell, alpha-beta