Preoperative chemotherapy as a predisposing factor for colonization of upper respiratory tract with Candida spp. in patients with non-small cell lung cancer

Ann Univ Mariae Curie Sklodowska Med. 2003;58(2):42-6.

Abstract

In the present study 48 patients with non-small cell lung cancer (NSCLC) were included--20 patients from control group and 28 patients after at least one course of preoperative chemotherapy. The analysis of nasopharyngeal microflora in these patients suggests that preoperative chemotherapy can be regarded as a predisposing factor for colonization of mucous membrane of throat with yeast-like fungi--Candida spp.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects*
  • Candida / isolation & purification*
  • Carcinoma, Non-Small-Cell Lung / drug therapy*
  • Carcinoma, Non-Small-Cell Lung / surgery
  • Chemotherapy, Adjuvant / adverse effects
  • Female
  • Humans
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / surgery
  • Male
  • Middle Aged
  • Nasopharynx / microbiology
  • Neoadjuvant Therapy / adverse effects*
  • Neoadjuvant Therapy / methods
  • Respiratory System / microbiology*
  • Treatment Outcome