A complete and durable clinical response to high-dose dexamethasone in a patient with scleromyxedema

J Am Acad Dermatol. 2004 Aug;51(2 Suppl):S120-3. doi: 10.1016/j.jaad.2004.03.023.

Abstract

We report a case of a patient with scleromyxedema limited to the skin with an associated IgG lambda monoclonal protein treated successfully with high-dose dexamethasone. We encourage the continued investigation of this complex relationship between the clinical presentation of scleromyxedema and its frequently associated paraproteinemia.

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • Dexamethasone / administration & dosage*
  • Drug Administration Schedule
  • Humans
  • Male
  • Middle Aged
  • Scleroderma, Diffuse / diagnosis
  • Scleroderma, Diffuse / drug therapy*
  • Scleroderma, Diffuse / pathology
  • Skin / pathology

Substances

  • Dexamethasone