Monanchorin, a bicyclic alkaloid from the sponge Monanchora ungiculata

Karina M Meragelman; Tawnya C McKee; James B McMahon

doi:10.1021/np030434i

Monanchorin, a bicyclic alkaloid from the sponge Monanchora ungiculata

J Nat Prod. 2004 Jul;67(7):1165-7. doi: 10.1021/np030434i.

Authors

Karina M Meragelman¹, Tawnya C McKee, James B McMahon

Affiliation

¹ Molecular Targets Development Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702-1201, USA.

PMID: 15270573
DOI: 10.1021/np030434i

Abstract

Monanchorin, a guanidine alkaloid with an unusual bicyclic skeleton, together with the known pentacyclic alkaloid crambescidin acid have been isolated from the aqueous extract of the sponge Monanchoraungiculata.

Publication types

Research Support, U.S. Gov't, P.H.S.

MeSH terms

Alkaloids / chemistry*
Alkaloids / isolation & purification*
Animals
Bridged Bicyclo Compounds, Heterocyclic / chemistry*
Bridged Bicyclo Compounds, Heterocyclic / isolation & purification*
Bridged Bicyclo Compounds, Heterocyclic / pharmacology
Guanidine
Guanidines / chemistry
Guanidines / isolation & purification*
Guanidines / pharmacology
Inhibitory Concentration 50
Mast Cells / drug effects
Mice
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Pacific Ocean
Porifera / chemistry*

Substances

Alkaloids
Bridged Bicyclo Compounds, Heterocyclic
Guanidines
monanchorin
Guanidine