Sclerosing epithelioid fibrosarcoma with der(10)t(10;17)(p11;q11)

Cancer Genet Cytogenet. 2004 Jul 15;152(2):136-40. doi: 10.1016/j.cancergencyto.2003.11.007.

Abstract

Sclerosing epithelioid fibrosarcoma is a recently described, rare mesenchymal neoplasm. We report a case of sclerosing epithelioid fibrosarcoma that occurred in the lower leg of a 48-year-old man. The karyotype of the tumor exhibited der(1)t(1;10)(p31;p11), der(10)t(10;17)(p11;q11), and der(17) t(11;17)(?;q11). Rearrangement of 10p11 was also found in one previous reported case of this uncommon tumor.

Publication types

  • Case Reports

MeSH terms

  • Chromosome Aberrations
  • Chromosomes, Human, Pair 10 / genetics*
  • Chromosomes, Human, Pair 17 / genetics*
  • Epithelioid Cells / pathology*
  • Fibrosarcoma / genetics*
  • Fibrosarcoma / pathology
  • Gene Rearrangement*
  • Humans
  • Karyotyping
  • Leg
  • Male
  • Middle Aged
  • Reverse Transcriptase Polymerase Chain Reaction
  • Soft Tissue Neoplasms / genetics*
  • Soft Tissue Neoplasms / pathology
  • Translocation, Genetic / genetics*