Idiopathic granulomatous vulvitis

Australas J Dermatol. 2004 Aug;45(3):181-3. doi: 10.1111/j.1440-0960.2004.00085.x.

Abstract

A 20-year-old woman initially presented with clinical evidence of an acute vulval inflammatory disorder incorrectly diagnosed as a Bartholin's abscess. Prolonged healing associated with infection followed attempts to incise and biopsy the area. Over a decade the condition has followed a chronic course with exacerbations and remissions and the vulva has become progressively more swollen and distorted. Lymphangiomas have developed. Histology showed non-necrotizing granulomas. Investigations for Crohn's disease and sarcoidosis were negative. Prednisone resulted in improvement during acute inflammatory episodes.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Inflammatory Agents / therapeutic use
  • Female
  • Humans
  • Melkersson-Rosenthal Syndrome / complications
  • Melkersson-Rosenthal Syndrome / diagnosis
  • Melkersson-Rosenthal Syndrome / drug therapy
  • Melkersson-Rosenthal Syndrome / pathology*
  • Prednisone / therapeutic use
  • Vulvitis / complications
  • Vulvitis / diagnosis
  • Vulvitis / drug therapy
  • Vulvitis / pathology*

Substances

  • Anti-Inflammatory Agents
  • Prednisone