Abstract
We report the case of a 41-Year-old man presenting with hepatic vein thrombosis (Budd-Chiari syndrome) during Infliximab therapy for ankylosing spondylitis. The systematic work-up revealed paroxysmal nocturnal hemoglobinuria. One Year later the patient was receiving anticoagulation therapy and was in good condition. The role of Infliximab in the development of thrombosis in this patient with rare underlying thrombophilia is discussed.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Adult
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Antibodies, Monoclonal / adverse effects
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Antibodies, Monoclonal / therapeutic use
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Budd-Chiari Syndrome / chemically induced*
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Budd-Chiari Syndrome / complications*
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Budd-Chiari Syndrome / diagnosis
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Diagnosis, Differential
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Gastrointestinal Agents / adverse effects
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Gastrointestinal Agents / therapeutic use
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Hemoglobinuria, Paroxysmal / etiology*
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Humans
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Infliximab
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Male
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Spondylitis, Ankylosing / drug therapy
Substances
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Antibodies, Monoclonal
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Gastrointestinal Agents
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Infliximab