Epidemiological investigation of bloodstream infections by extended spectrum cephalosporin-resistant Escherichia coli in a Taiwanese teaching hospital

J Clin Microbiol. 2004 Jul;42(7):3329-32. doi: 10.1128/JCM.42.7.3329-3332.2004.

Abstract

In an epidemiologic and case-control study including 30 case patients over a 3.5-year period in a Taiwanese university hospital, only beta-lactamase inhibitor use and extended-spectrum cephalosporin use were identified as independent risk factors for nosocomial CMY-2-producing Escherichia coli bloodstream infection, and CMY-2 producers were found more prevalent than extended-spectrum beta-lactamase-producing isolates.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Bacteremia / epidemiology
  • Bacteremia / etiology*
  • Case-Control Studies
  • Cephalosporin Resistance*
  • Escherichia coli / drug effects*
  • Escherichia coli / enzymology
  • Escherichia coli Infections / epidemiology
  • Escherichia coli Infections / etiology*
  • Female
  • Hospitals, Teaching
  • Humans
  • Male
  • Middle Aged
  • Random Amplified Polymorphic DNA Technique
  • Risk Factors
  • Taiwan / epidemiology
  • beta-Lactamases / biosynthesis*

Substances

  • beta-lactamase CMY-2
  • beta-Lactamases