Three-dimensional echocardiography-guided atrial septectomy: an experimental study

J Thorac Cardiovasc Surg. 2004 Jul;128(1):53-9. doi: 10.1016/j.jtcvs.2004.03.008.

Abstract

Objectives: The surgical feasibility of beating-heart atrial septectomy under the guidance of two different types of real-time 3-dimensional echocardiography systems was examined.

Methods: A modified real-time 3-dimensional echocardiography system with a x4 matrix transducer (Sonos 7500; Philips Medical Systems, Andover, Mass) or a mechanical 1-dimensional array transducer (SSD-5500; Aloka Co, Ltd, Tokyo, Japan) was used. Small porcine atrial septal defects (n = 8) were enlarged with a Kerrison bone punch in the tank model. In the animal studies, small atrial septal defects (n = 8) were enlarged with the same device through a transatrial port. In both experiments, the area of the atrial septal defect measured by real-time 3-dimensional echocardiography was compared with the area measured directly.

Results: Real-time 3-dimensional echocardiography provided satisfactory images and sufficient anatomic detail for the atrial septectomy in both experimental settings. All the atrial septal defects were successfully enlarged; an increase of as much as 293% of the preoperative atrial septal defect area was achieved in the tank experiment, and an increase of as great as 449% of the preoperative area was achieved in the animal experiment. The size of the atrial shunt was increased significantly after the atrial septectomy relative to that before the surgery (P <.0001). The percentage enlargement of the atrial septal defect measured by real-time 3-dimensional echocardiography was strongly correlated with that measured directly (both r(2) = 0.997, P <.0001) Bland-Altman analysis showed close agreement between the results obtained by the two measurement methods in both models.

Conclusions: Real-time 3-dimensional echocardiography provides satisfactory images and sufficient anatomic detail for atrial septectomy. This experiment demonstrates the surgical feasibility of a beating-heart intracardiac procedure such as atrial septectomy under real-time 3-dimensional echocardiographic guidance.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Cardiac Surgical Procedures*
  • Computer Systems
  • Coronary Vessels / diagnostic imaging
  • Coronary Vessels / pathology
  • Coronary Vessels / surgery
  • Disease Models, Animal
  • Dogs
  • Echocardiography, Three-Dimensional* / methods
  • Equipment Design
  • Heart Atria / diagnostic imaging
  • Heart Atria / pathology
  • Heart Atria / surgery
  • Heart Septal Defects, Atrial / diagnostic imaging
  • Heart Septal Defects, Atrial / surgery
  • Heart Septum / diagnostic imaging
  • Heart Septum / pathology
  • Heart Septum / surgery*
  • Models, Cardiovascular
  • Swine
  • Tricuspid Valve / diagnostic imaging
  • Tricuspid Valve / pathology
  • Tricuspid Valve / surgery