Germline mutations of the E-cadherin(CDH1) and TP53 genes, rather than of RUNX3 and HPP1, contribute to genetic predisposition in German gastric cancer patients

J Med Genet. 2004 Jun;41(6):e89. doi: 10.1136/jmg.2003.015594.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • CHO Cells
  • Cadherins / genetics*
  • Core Binding Factor Alpha 3 Subunit
  • Cricetinae
  • Cricetulus
  • DNA / chemistry
  • DNA / genetics
  • DNA Mutational Analysis / methods
  • DNA-Binding Proteins / genetics
  • Family Health
  • Female
  • Genetic Predisposition to Disease / genetics*
  • Germ-Line Mutation*
  • Humans
  • Immunohistochemistry
  • Male
  • Membrane Proteins / genetics
  • Neoplasm Proteins / genetics
  • Pedigree
  • Stomach Neoplasms / genetics*
  • Stomach Neoplasms / pathology
  • Transcription Factors / genetics
  • Tumor Suppressor Protein p53 / analysis
  • Tumor Suppressor Protein p53 / genetics*

Substances

  • Cadherins
  • Core Binding Factor Alpha 3 Subunit
  • DNA-Binding Proteins
  • Membrane Proteins
  • Neoplasm Proteins
  • Runx3 protein, human
  • TMEFF2 protein, human
  • Transcription Factors
  • Tumor Suppressor Protein p53
  • DNA