Etiologies of associations between childhood sleep and behavioral problems in a large twin sample

J Am Acad Child Adolesc Psychiatry. 2004 Jun;43(6):744-51. doi: 10.1097/01.chi/0000122798.47863.a5.

Abstract

Objective: To examine the etiologies of covariation of childhood sleep problems and other behavioral/emotional problems in young children.

Method: The parents of more than 6,000 twin pairs provided information on their twins' anxiety, conduct, and hyperactivity at ages 3, 4, and 7 by completing the Strengths and Difficulties Questionnaire. Information on sleep problems was obtained at age 3/4.

Results: Phenotypic correlations in preschool years between sleep problems and anxiety, conduct, and hyperactivity ranged from 0.17 to 0.22. These correlations were largely due to shared environmental factors (0.72-0.96) and less to heredity (0.05-0.26) and nonshared environment (0.00-0.06). Sleep problems at age 3/4 years predicted at age 7 years anxiety (beta =.12, p <.001), conduct problems (beta =.09, p <.001), and hyperactivity (beta =.07, p <.001), after accounting for stability of these problems. These predictive associations were also mainly mediated by shared environment (0.16-0.91), although genetic (0.02-0.84) and nonshared environmental (-0.03-0.09) factors were also influential.

Conclusions: The modest associations between early sleep problems and later behavioral/emotional problems are largely accounted for by common psychosocial risk factors. Further research on which specific risks may mediate these connections is needed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Twin Study

MeSH terms

  • Analysis of Variance
  • Child
  • Child Behavior Disorders / epidemiology
  • Child Behavior Disorders / etiology*
  • Child Behavior Disorders / genetics
  • Child, Preschool
  • Comorbidity
  • Diseases in Twins / epidemiology
  • Diseases in Twins / etiology*
  • Diseases in Twins / genetics
  • Female
  • Humans
  • Linear Models
  • Longitudinal Studies
  • Male
  • Models, Genetic
  • Sleep Wake Disorders / epidemiology
  • Sleep Wake Disorders / etiology*
  • Sleep Wake Disorders / genetics
  • United Kingdom / epidemiology