JTT-705. Japan Tobacco

Curr Opin Investig Drugs. 2004 Mar;5(3):339-43.

Abstract

JTT-705 is a cholesteryl ester transfer protein inhibitor under development by Japan Tobacco Inc for the treatment of hyperlipidemia. The compound is undergoing phase I clinical trials in Japan and phase II clinical trials in Europe.

Publication types

  • Review

MeSH terms

  • Amides
  • Animals
  • Clinical Trials, Phase I as Topic
  • Clinical Trials, Phase II as Topic
  • Esters
  • Humans
  • Hyperlipidemias / drug therapy
  • Hypolipidemic Agents / chemical synthesis
  • Hypolipidemic Agents / chemistry*
  • Hypolipidemic Agents / pharmacokinetics
  • Structure-Activity Relationship
  • Sulfhydryl Compounds / chemical synthesis
  • Sulfhydryl Compounds / chemistry*
  • Sulfhydryl Compounds / pharmacokinetics

Substances

  • Amides
  • Esters
  • Hypolipidemic Agents
  • Sulfhydryl Compounds
  • dalcetrapib