Rehospitalization after pediatric living-donor liver transplantation

Transplantation. 2004 Mar 27;77(6):880-5. doi: 10.1097/01.tp.0000116566.98067.7e.

Abstract

Background: Although rehospitalization is one of the factors affecting quality of life after successful liver transplantation, the effects of rehospitalization have not been assessed to date.

Patients and methods: Of 40 consecutive cases of pediatric living-donor liver transplantation (LDLT) performed between April 1994 and October 2000, 28 patients with a graft survival of more than 1 year were enrolled in this study to examine rehospitalization after successful LDLT. The rate and cause of rehospitalization were analyzed retrospectively on the basis of medical records.

Results: A total of 23 of the 28 patients were rehospitalized. There were 84 episodes of rehospitalization. The mean number of rehospitalization days per episode per patient was 21.06 +/- 21.02 days. The rate of total rehospitalization days to the days after the hospitalization for LDLT was 6.56% +/- 8.73%. Rehospitalization episodes were attributable to the following: cholangitis (21.4%), viral infection (16.7%), and portal stenosis (PS) (13.1%). Rehospitalization as the result of rejection accounted for 9.5% of the episodes. The period of rehospitalization was long in the case of cholangitis (49.7 +/- 62.4 days), PS (13.8 +/- 13.4 days), and rejection (52.9 +/- 45.4 days). Although there were a lot of rehospitalization episodes as the result of viral infection subsequent to cholangitis, each rehospitalization period lasted 4.4 +/- 6.6 days.

Conclusion: It is suggested that prevention of cholangitis and PS, which were the causes of frequent and long rehospitalization periods, would result in a reduction of rehospitalization and therefore a better quality of life after pediatric LDLT.

MeSH terms

  • Adult
  • Child
  • Child, Preschool
  • Cholangitis / epidemiology
  • Female
  • Graft Rejection / epidemiology
  • Graft Survival
  • Humans
  • Liver Transplantation / statistics & numerical data*
  • Living Donors*
  • Male
  • Patient Readmission / statistics & numerical data*
  • Postoperative Complications / epidemiology*
  • Retrospective Studies
  • Virus Diseases / epidemiology