(Z)-3-(1-Methyl-1H-indol-3-yl)-2-(thiophen-3-yl)acrylonitrile

Acta Crystallogr C. 2004 Mar;60(Pt 3):o217-8. doi: 10.1107/S0108270104002550. Epub 2004 Feb 19.

Abstract

The title compound, C16H12N2S, has been synthesized by base-catalyzed condensation of 1-methylindole-3-carboxaldehyde with thiophene-3-acetonitrile. The product assumes an approximately planar Z configuration. The molecule has a thienyl-ring flip disorder.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acrylonitrile / analogs & derivatives*
  • Acrylonitrile / chemical synthesis
  • Acrylonitrile / chemistry*
  • Antitubercular Agents / chemistry
  • Crystallography, X-Ray
  • Hydrogen Bonding
  • Indoles / chemistry*
  • Molecular Conformation
  • Molecular Structure
  • Stereoisomerism
  • Thiophenes / chemical synthesis
  • Thiophenes / chemistry*

Substances

  • 3-(1-methyl-1H-indol-3-yl)-2-(thiophen-3-yl)acrylonitrile
  • Antitubercular Agents
  • Indoles
  • Thiophenes
  • Acrylonitrile