Maintaining or breaking CD8+ T-cell tolerance to beta islet cell antigens: lessons from transgenic mouse models

J Autoimmun. 2004 Mar;22(2):115-20. doi: 10.1016/j.jaut.2003.10.004.

Authors

Eliane Piaggio¹, Agnès Hartemann-Heurtier, Julie Cabarrocas, Sabine Desbois, Lennart T Mars, Jacques P Zappulla, Roland S Liblau

Affiliation

¹ INSERM U563, Purpan University Hospital, Place Dr Baylac, Toulouse 31000, France.

PMID: 14987739
DOI: 10.1016/j.jaut.2003.10.004

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Autoantigens / immunology*
Autoimmunity / genetics
Autoimmunity / immunology*
B-Lymphocytes / immunology
CD4-Positive T-Lymphocytes / immunology
CD8-Positive T-Lymphocytes / immunology*
Diabetes Mellitus, Type 1 / genetics
Diabetes Mellitus, Type 1 / immunology*
Disease Models, Animal
Humans
Islets of Langerhans / immunology*
Killer Cells, Natural / immunology
Macrophages / immunology
Major Histocompatibility Complex / genetics
Major Histocompatibility Complex / immunology
Mice
Mice, Transgenic
Self Tolerance / immunology*
T-Lymphocyte Subsets / immunology

Substances

Autoantigens