Growth hormone response to clonidine in male patients with panic disorder untreated by antidepressants

Psychol Med. 1992 Nov;22(4):1059-62. doi: 10.1017/s0033291700038630.

Abstract

We report a non-significantly higher growth hormone (GH) response to intravenous clonidine administration (150 micrograms) in 10 male patients with panic disorder who had never received antidepressant therapy than in 10 matched controls. These results are consistent with data suggesting a normal or increased adrenergic receptor sensitivity in panic disorder patients.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Clonidine / administration & dosage
  • Clonidine / metabolism
  • Clonidine / therapeutic use*
  • Growth Hormone-Releasing Hormone / blood
  • Growth Hormone-Releasing Hormone / drug effects*
  • Humans
  • Injections, Intravenous
  • Male
  • Middle Aged
  • Panic Disorder / blood
  • Panic Disorder / drug therapy*
  • Panic Disorder / metabolism
  • Receptors, Adrenergic / drug effects
  • Receptors, Adrenergic / metabolism

Substances

  • Receptors, Adrenergic
  • Growth Hormone-Releasing Hormone
  • Clonidine