[Prolonged hepatitis A: three case reports]

Mikrobiyol Bul. 2003 Oct;37(4):301-7.
[Article in Turkish]

Abstract

In this report, three patients, admitted to Ankara University Faculty of Medicine, Ibni Sina Hospital, Clinical Bacteriology and Infectious Diseases Department, with the diagnosis of acute viral hepatitis A have been discussed because of their clinical and/or biochemical relapses. Following conservative treatment and bedrest, the liver transaminases decrease to nearly normal levels but a second peak was observed later in three of the cases. Other viral, metabolic and autoimmune factors which could lead to the increase of liver transaminases were ruled out. Anti-HAV IgM antibodies became negative in 2 to 4 months later, and liver enzymes returned to normal in 4 to 5 months after onset of their illnesses. As a result, it was concluded that conservative follow-up and therapy would be sufficient since the prognosis of A hepatitis is usually benign even if it relapsed.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Acute Disease
  • Adolescent
  • Adult
  • Female
  • Hepatitis A / diagnosis*
  • Hepatitis A / therapy
  • Hepatitis A Antibodies / blood
  • Humans
  • Liver / enzymology
  • Male
  • Prognosis
  • Recurrence
  • Transaminases / blood

Substances

  • Hepatitis A Antibodies
  • Transaminases