Enantioselective hydrolysis of various substituted styrene oxides with Aspergillus Niger CGMCC 0496

Hao Jin; Zu-Yi Li; Xiao-Wei Dong

doi:10.1039/b312469j

Enantioselective hydrolysis of various substituted styrene oxides with Aspergillus Niger CGMCC 0496

Org Biomol Chem. 2004 Feb 7;2(3):408-14. doi: 10.1039/b312469j. Epub 2004 Jan 12.

Authors

Hao Jin¹, Zu-Yi Li, Xiao-Wei Dong

Affiliation

¹ State Key Laboratory of Bioorganic & Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, China. lizy@mail.sioc.ac.cn

PMID: 14747870
DOI: 10.1039/b312469j

Abstract

Enantioselective biohydrolysis of various substituted styrene oxides using whole fungus cells of Aspergillus nigerCGMCC 0496 are described. The results show not only para- but also some ortho- substituted styrene oxides can achieve high enantioselectivity during the hydrolysis.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aspergillus niger / enzymology
Aspergillus niger / metabolism*
Biotransformation
Epoxy Compounds / chemistry*
Epoxy Compounds / metabolism*
Hydrolysis
Molecular Structure
Stereoisomerism
Temperature

Substances

Epoxy Compounds
styrene oxide