FDG-PET for evaluation of recurrent lymph node metastases in patients with surgically resected breast cancer: adding spot images to whole body images

Breast Cancer. 2004;11(1):60-4. doi: 10.1007/BF02968004.

Abstract

Background: To evaluate the role of 18F-Fluorodeoxyglucose positron emission tomography (FDG-PET), spot images were added to whole-body FDG-PET images in a patient with suspected lymph node recurrence of breast cancer.

Methods: FDG-PET spot images were obtained of 44 patients who had undergone surgical resection of breast cancer as were whole-body FDG-PET images. A total of 33 lesions in 19 patients (mean age, 59 years; range, 39-70 years) were diagnosed as lymph node recurrence clinically, and standardized uptake values (SUVs) were calculated for whole body images and spot images. Lesions were also scored from 1 (not clear) to 3 (very clear) for both the whole body and spot images.

Results: For mediastinal lymph node metastases, the SUVs of the spot images (SUVsp) (mean, 4.0; range, 2.1-6.6) were significantly higher than the SUVs of the whole body images (SUVwb) (mean, 3.3; range, 2.1-5.8). For other lymph node metastases (neck, axilla, etc.), there was no significant difference between SUVwb (2.6; 1.4-6.5) and SUVsp (2.8; 1.6-8.1).

Conclusions: By adding spot images, the evaluation of lymph node metastases became easier. Adding spot images to whole-body FDG-PET may be useful.

MeSH terms

  • Adult
  • Aged
  • Breast Neoplasms / diagnosis*
  • Breast Neoplasms / surgery
  • Female
  • Fluorodeoxyglucose F18
  • Humans
  • Lymphatic Metastasis
  • Mastectomy
  • Middle Aged
  • Neoplasm Recurrence, Local / diagnosis*
  • Radiopharmaceuticals
  • Tomography, Emission-Computed / methods*

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18