Structure and electronic properties of an asymmetric thiolate-bridged binuclear complex: a model for the active site of acetyl CoA synthase

Chem Commun (Camb). 2003 Dec 21:(24):3012-3. doi: 10.1039/b310183e.

Abstract

The asymmetric binuclear complex [(dppe)Ni(mu-'S, S')Ni(L)](PF6)2 [L = (N, N'-diethyl-3,7-diazanonane-1,9-dithiolato)2-] shows a reversible one-electron reduction to afford a mixed-valent Ni(II) x Ni(I) species; the reduced complex has been characterised by EPR spectroscopy and mimics the redox active Nip site in the active A-cluster of acetyl coenzyme A synthase.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehyde Oxidoreductases / chemistry*
  • Binding Sites
  • Biomimetic Materials / chemistry
  • Bridged-Ring Compounds / chemistry*
  • Electron Spin Resonance Spectroscopy
  • Molecular Structure
  • Multienzyme Complexes / chemistry*
  • Nickel / chemistry
  • Organometallic Compounds / chemistry
  • Sulfhydryl Compounds / chemistry*

Substances

  • Bridged-Ring Compounds
  • Multienzyme Complexes
  • Organometallic Compounds
  • Sulfhydryl Compounds
  • Nickel
  • Aldehyde Oxidoreductases
  • carbon monoxide dehydrogenase