The role of hepatic Mrp2 in the interaction of flavopiridol and bilirubin: impact on therapy

Int J Clin Pharmacol Ther. 2003 Dec;41(12):610-1. doi: 10.5414/cpp41610.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • ATP-Binding Cassette Transporters*
  • Animals
  • Antineoplastic Agents / adverse effects*
  • Antineoplastic Agents / metabolism
  • Antineoplastic Agents / pharmacokinetics*
  • Carrier Proteins / pharmacology*
  • Disease Models, Animal
  • Drug Interactions
  • Flavonoids / adverse effects*
  • Flavonoids / metabolism
  • Flavonoids / pharmacokinetics*
  • Hyperbilirubinemia / chemically induced*
  • Hyperbilirubinemia / physiopathology
  • Male
  • Piperidines / adverse effects*
  • Piperidines / metabolism
  • Piperidines / pharmacokinetics*
  • Rats
  • Rats, Wistar

Substances

  • ATP-Binding Cassette Transporters
  • Abcc2 protein, rat
  • Antineoplastic Agents
  • Carrier Proteins
  • Flavonoids
  • Piperidines
  • alvocidib