Phenotypic features of Huntington's disease-like 2

Mov Disord. 2003 Dec;18(12):1527-30. doi: 10.1002/mds.10587.

Abstract

Huntington's disease-like 2 is an autosomal dominantly inherited disorder due to an expansion of trinucleotide repeats. It resembles classic Huntington's disease in clinical phenotype, inheritance pattern, and neuropathological features. We highlight the clinical features of this disorder, including chorea, dystonia, parkinsonism, and cognitive deficits.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Atrophy / pathology
  • Brain / pathology*
  • Cognition Disorders / diagnosis
  • Female
  • Humans
  • Huntington Disease / genetics*
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Phenotype
  • Trinucleotide Repeat Expansion / genetics*
  • Videotape Recording