[Clinical evaluation of bronchial asthma complicated with sarcoidosis]

Nihon Kokyuki Gakkai Zasshi. 2003 Nov;41(11):777-80.
[Article in Japanese]

Abstract

The clinical features of 25 asthma cases complicated with sarcoidosis were evaluated retrospectively. In our department, 8 patients (6%) out of 134 with sarcoidosis had asthma. The complication was found more frequently in females than in males, and the age of onset of the asthma extended from 2 to 63 years. Neither the severity nor the type of asthma showed any distinct pattern. In terms of chest radiographs of sarcoidosis, stage II was more common in our cases, while stage I was more common in the reported cases. In our cases, the severity of the asthma remained stable irrespective of the activity of the sarcoidosis. In the reported cases, the two diseases showed similar courses. The deterioration of each disease was associated in few cases with improvement in the other. In summary, the present study suggests that inflammation of the airways in asthma and sarcoidosis probably affect their course so that the two diseases improve or deteriorate together.

MeSH terms

  • Adolescent
  • Adult
  • Age of Onset
  • Asthma / complications*
  • Asthma / epidemiology
  • Asthma / physiopathology
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Lung Diseases / complications*
  • Lung Diseases / diagnostic imaging
  • Lung Diseases / physiopathology
  • Male
  • Middle Aged
  • Retrospective Studies
  • Sarcoidosis / complications*
  • Sarcoidosis / diagnostic imaging
  • Sarcoidosis / epidemiology
  • Sarcoidosis / physiopathology
  • Severity of Illness Index
  • Sex Factors
  • Tomography, X-Ray Computed