The aim of the study was to characterize mental changes in chronic prostatitis (CP) patients after the addition of a combination of local and central reflex physiotherapeutic factors to combined treatment 149 patients with infectious and noninfectious CP entered the study. The study group (n = 94) received combined treatment including physiotherapeutic factors (ANDRO-GIN unit). The control group (n = 55) received standard CP therapy. All the patients have undergone clinical, laboratory, device and psychophysiological examinations. Thus, addition of physiotherapy to combined treatment of CP raises the treatment efficacy and promotes optimization of "an internal picture of illness"--one of major characteristics of the patient's psychological condition.